8: Izvori

Priključenija
Miloševa hijearhija izvora:

Viber, Whatsapp, Fejsbuk, Tviter i ostale društvene mreže 💩💩
Portali 💩
Dnevne novine ❓❓❓
Nedeljne i mesečne publikacije ⬅️ bolje je pratiti novinara

Bonus: dve osobe koje znaju o čemu pišu (na engleskom)

Zeynep Tufekci
Ed Yong

Bonus 2: Neki članci Financial Times-a o pandemiji su besplatni

Miloševa hijearhija izvora:
* Viber, Whatsapp, Fejsbuk, Tviter i ostale društvene mreže 💩💩
* Portali 💩
* Dnevne novine ❓❓❓
* Nedeljne i mesečne publikacije ⬅️ bolje je pratiti novinara
Bonus: dve osobe koje znaju o čemu pišu (na engleskom)
* Zeynep Tufekci (https://twitter.com/zeynep)
* Ed Yong (https://twitter.com/edyong209)
Bonus 2: Neki članci Financial Times-a o pandemiji su besplatni (https://www.ft.com/coronavirusfree)

7: Terapija 2

Priključenija
Blic: KAUBOJSKA MEDICINA NE DAJE REZULTATE ← naslov njihov, ali nije pogrešan
NEJM: Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report ← RECOVERY studija, deksametazon
NEJM: Remdesivir for the Treatment of Covid-19 — Preliminary Report ← NIAID studija, remdesivir
Youtube: Pravilna upotreba zaštitne maske ← uputstvo Crvenog Krsta
Blic: KAUBOJSKA MEDICINA NE DAJE REZULTATE (https://www.blic.rs/vesti/drustvo/kaubojska-medicina-ne-daje-rezultate-srpski-naucnici-iz-amerike-objasnjavaju-koja-dva/vg4shsv) ← naslov njihov, ali nije pogrešan
NEJM: Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report (https://www.nejm.org/doi/10.1056/NEJMoa2021436) ← RECOVERY studija, deksametazon
NEJM: Remdesivir for the Treatment of Covid-19 — Preliminary Report (https://www.nejm.org/doi/full/10.1056/NEJMoa2007764) ← NIAID studija, remdesivir
Youtube: Pravilna upotreba zaštitne maske (https://www.youtube.com/watch?v=FvWF8N-bzho) ← uputstvo Crvenog Krsta

5: Kratko predavanje

Priključenija
Nebojša je odsutan.
Nebojša je odsutan. Miloš pokušava da prevede svoje predavanje o Covid-19 i pacijentima sa rakom na srpski.
Izvori:
1. Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270–3.
2. Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science. 2020:eabb2762.
3. Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh C-L, Abiona O, et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. 2020;367(6483):1260–3.
4. van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med. 2020.
5. Li R, Pei S, Chen B, Song Y, Zhang T, Yang W, et al. Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2). Science. 2020:eabb3221.
6. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet (London, England). 2020
7. Chen G, Wu D, Guo W, Cao Y, Huang D, Wang H, et al. Clinical and immunologic features in severe and moderate Coronavirus Disease 2019. J Clin Invest. 2020.
8. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. Jama. 2020.
9. Docherty AB, Harrison EM, Green CA, Hardwick HE, Pius R, Norman L, et al. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. medRxiv. 2020:2020.04.23.20076042.
10. Collaborative TO, Williamson E, Walker AJ, Bhaskaran KJ, Bacon S, Bates C, et al. OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. medRxiv. 2020:2020.05.06.20092999.
11. Zhang L, Zhu F, Xie L, Wang C, Wang J, Chen R, et al. Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China. Ann Oncol. 2020.
12. Dai M, Liu D, Liu M, Zhou F, Li G, Chen Z, et al. Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak. Cancer Discov. 2020.
Linkovi:
1. The Covid-19 and cancer consortium (https://ccc19us.org)
2. ASCO Covid-19 resources (https://www.asco.org/asco-coronavirus-information)
3. ASH Covid-19 resources (https://www.hematology.org/covid-19)

4: Vuhanski virus

Priključenija
Koje je poreklo virusa SARS-CoV-2?
Koje je poreklo virusa SARS-CoV-2? Od 5G mreža preko bega iz laboratorije do najverovatnijeg odgovora: slepih miševa, pangolina, i nesposobnosti svetskih vlada da preduprede najočigledniju moguću katastrofu.
Virusi slični SARS-u u slepim miševima u Kini (https://www.nature.com/articles/nm.3985), rad iz 2015-te (Nature Medicine)
Sekvenciranje SARS-CoV-2 u uzorcima iz Vuhana (https://www.nature.com/articles/s41586-020-2012-7) (Nature)
Poreklo SARS-CoV-2, mišljenje vir(us)ologa (https://www.nature.com/articles/s41591-020-0820-9) (Nature Medicine)
Bonus:
* Intervju sa Lerijem Brilijantom, epidemiologom koji je savetovao Stivena Sodeberga (https://www.wired.com/story/coronavirus-interview-larry-brilliant-smallpox-epidemiologist/) (Wired)
* Jelena Đoković i 5G mreže (https://luftika.rs/jelena-djokovic-5g-mreza-koronavirus/) (Luftika(!?))

3: Terapija

Priključenija
Vidi li se kraj pandemije?
Vidi li se kraj pandemije? Ne bez leka. Govorimo o tri do sada objavljene studije.
Hidroksihlorokvin i azitromicin za COVID-19, francuska (nazovi) studija (https://www.sciencedirect.com/science/article/pii/S0924857920300996)
Lopinavir i ritonavir za teško obolele od COVID-19, randomizirana studija iz Kine (https://www.nejm.org/doi/full/10.1056/NEJMoa2001282) (NEJM)
Plazma preležalih od COVID-19 za pet pacijenata na intenzivnoj nezi, mala ali dobra studija iz Kine (https://jamanetwork.com/journals/jama/fullarticle/2763983) (JAMA)
Američki Nacionalni projekat za rekonvalescentnu plazmu (https://ccpp19.org/)

2: Sve preduzete mere

Priključenija
Sa smanjenim brojem pacijenata na klinici, imamo vremena za čitanje (i komentarisanje) radova o novom koronavirusu: jedan epidemiološki model, jedna jednostavna studija o preživljavanju virusa u vazduhu na različitim površinama, jedna serija slučajeva bolničkog lečenja iz Kine, i nekoliko saveta o maskama, lekovima, i dezinfekciji.
Sa smanjenim brojem pacijenata na klinici, imamo vremena za čitanje (i komentarisanje) radova o novom koronavirusu: jedan epidemiološki model, jedna jednostavna studija o preživljavanju virusa u vazduhu na različitim površinama, jedna serija slučajeva bolničkog lečenja iz Kine, i nekoliko saveta o maskama, lekovima, i dezinfekciji.
Model zbog kojeg je Velika Britanija promenila svoju strategiju: Impact of non-pharmaceutical interventions (NPIs) to reduce COVID- 19 mortality and healthcare demand (https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf) (PDF)
Koliko dugo SARS-CoV-2 može da preživi u vazduhu, na plastici, nerđajućem čeliku, bakru, i kartonu? Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 (https://www.nejm.org/doi/full/10.1056/NEJMc2004973) (NEJM)
Meta-analiza efikasnosti različitih sredstava za dezinfekciju na SARS-CoV-1 i endemske koronaviruse (ali ne i SARS-CoV-2). Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents (https://www.sciencedirect.com/science/article/pii/S0195670120300463) (JHIN)
Ishodi kineskih pacijenata na bolničkom lečenju. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30566-3/fulltext) (Lancet)
I ne zaboravite: nismo ekonomisti, epidemiolozi, ni virolozi, ali jesmo lekari.

1: Vanredno stanje

Priključenija
Nismo epidemiolozi, a ni virolozi, ali umemo da pričamo. Šta dva onkologa misle da znaju o koronavirusu?
Nismo epidemiolozi, a ni virolozi, ali umemo da pričamo. Šta dva onkologa misle da znaju o koronavirusu?
Nebojša (https://twitter.com/SkorupanMD) počinje i završava. U sredinu, dosta pretpostavki i nedovoljno činjenica, uglavnom od Miloša (https://twitter.com/miljko).
Za prave savete o pripremama za karantin koje je napisao neko ko je to već preživeo, pratite @amfibolije (https://twitter.com/amfibolije) na Tviteru.